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Standardization of RNA Chemical Mapping Experiments
[Image: see text] Chemical mapping experiments offer powerful information about RNA structure but currently involve ad hoc assumptions in data processing. We show that simple dilutions, referencing standards (GAGUA hairpins), and HiTRACE/MAPseeker analysis allow rigorous overmodification correction,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033625/ https://ncbi.nlm.nih.gov/pubmed/24766159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5003426 |
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