T cells expressing chimeric antigen receptor promote immune tolerance

Cellular therapies based on permanent genetic modification of conventional T cells have emerged as a promising strategy for cancer. However, it remains unknown if modification of T cell subsets, such as Tregs, could be useful in other settings, such as allograft transplantation. Here, we use a modul...

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Publicat a:JCI Insight
Autors principals: Pierini, Antonio, Iliopoulou, Bettina P., Peiris, Heshan, Pérez-Cruz, Magdiel, Baker, Jeanette, Hsu, Katie, Gu, Xueying, Zheng, Ping-Ping, Erkers, Tom, Tang, Sai-Wen, Strober, William, Alvarez, Maite, Ring, Aaron, Velardi, Andrea, Negrin, Robert S., Kim, Seung K., Meyer, Everett H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846896/
https://ncbi.nlm.nih.gov/pubmed/29046484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92865
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