Third-party CD4(+) invariant natural killer T cells protect from murine GVHD lethality

Graft-versus-host disease (GVHD) is driven by extensive activation and proliferation of alloreactive donor T cells causing significant morbidity and mortality following allogeneic hematopoietic cell transplantation (HCT). Invariant natural killer T (iNKT) cells are a potent immunoregulatory T-cell s...

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Publicado en:Blood
Autores principales: Schneidawind, Dominik, Baker, Jeanette, Pierini, Antonio, Buechele, Corina, Luong, Richard H., Meyer, Everett H., Negrin, Robert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2015
Materias:
Transplantation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447863/
https://ncbi.nlm.nih.gov/pubmed/25795920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-612762
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