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Valproic acid disrupts the biomechanics of late spinal neural tube closure in mouse embryos
Failure of neural tube closure in the early embryo causes neural tube defects including spina bifida. Spina bifida lesions predominate in the distal spine, particularly after exposure to the anticonvulsant valproic acid (VPA). How VPA specifically disturbs late stages of neural tube closure is uncle...
保存先:
| 出版年: | Mech Dev |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846844/ https://ncbi.nlm.nih.gov/pubmed/29225143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2017.12.001 |
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