Biomechanical coupling facilitates spinal neural tube closure in mouse embryos

Neural tube (NT) formation in the spinal region of the mammalian embryo involves a wave of “zippering” that passes down the elongating spinal axis, uniting the neural fold tips in the dorsal midline. Failure of this closure process leads to open spina bifida, a common cause of severe neurologic disa...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Galea, Gabriel L., Cho, Young-June, Galea, Gauden, Molè, Matteo A., Rolo, Ana, Savery, Dawn, Moulding, Dale, Culshaw, Lucy H., Nikolopoulou, Evanthia, Greene, Nicholas D. E., Copp, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495245/
https://ncbi.nlm.nih.gov/pubmed/28607062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700934114
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