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Synthesis and Evaluation of Pyridyloxypyridyl Indole Carboxamides as Potential PET Imaging Agents for 5-HT(2C) Receptors
[Image: see text] Nine pyridyloxypyridyl indole carboxamides were synthesized and displayed high affinities for 5-HT(2C) receptors and high selectivity over 5-HT(2A) and 5-HT(2B). Among them, 6-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]1H-indole-3-carboxamide (8) exhibits the highest 5-HT(...
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| I publikationen: | ACS Med Chem Lett |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Chemical
Society
2018
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846131/ https://ncbi.nlm.nih.gov/pubmed/29541358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00443 |
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