Design, Synthesis and Evaluation of Indole-2-carboxamides with Pan Anti-mycobacterial Activity

Current treatment regimens for non-tuberculous mycobacteria (NTM) and tuberculosis (TB) generally require long duration of therapy with multiple drugs, some of which are broad spectrum antibiotics. Despite some advances in antimicrobial compounds, there remains a need in therapy for antibiotics with...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Franz, Nicholas D., Belardinelli, Juan Manuel, Kaminski, Michael A., Dunn, Louis C., de Moura, Vinicius Calado Nogueira, Blaha, Michael A., Truong, Dan D., Li, Wei, Jackson, Mary, North, E. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539987/
https://ncbi.nlm.nih.gov/pubmed/28545813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.05.015
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