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Nanogel-DFO Conjugates as a Model to Investigate Pharmacokinetics, Biodistribution, and Iron Chelation In Vivo
Deferoxamine (DFO) to treat iron overload (IO) has been limited by toxicity issues and short circulation times and it would be desirable to prolong circulation to improve non-transferrin bound iron (NTBI) chelation. In addition, DFO is currently unable to efficiently target the large pool of iron in...
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| Wydane w: | Int J Pharm |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5845769/ https://ncbi.nlm.nih.gov/pubmed/29341909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.01.004 |
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