Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism

OBJECTIVES: To explore the functions of RUNX3 single nucleotide polymorphisms (SNPs) associated with ankylosing spondylitis (AS). METHODS: Individual SNP associations were evaluated in 4230 UK cases. Their effects on transcription factor (TF) binding, transcription regulation, chromatin modification...

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Detalhes bibliográficos
Publicado no:RMD Open
Main Authors: Vecellio, Matteo, Cortes, Adrian, Roberts, Amity R, Ellis, Jonathan, Cohen, Carla Jayne, Knight, Julian C, Brown, Matthew A, Bowness, Paul, Wordsworth, Bryan Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Spondyloarthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845418/
https://ncbi.nlm.nih.gov/pubmed/29531791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2017-000628
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