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Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis
OBJECTIVE: To investigate the functional consequences of the single‐nucleotide polymorphism rs4648889 in a putative enhancer upstream of the RUNX3 promoter associated with susceptibility to ankylosing spondylitis (AS). METHODS: Using nuclear extracts from Jurkat cells and primary human CD8+ T cells,...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8251554/ https://ncbi.nlm.nih.gov/pubmed/33369221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41628 |
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