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Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

BACKGROUND: The fibrillation of islet amyloid polypeptide (IAPP) triggered the amyloid deposition, then enhanced the loss of the pancreatic islet mass. However, it is not clear what factor is the determinant in development of the fibril formation. The aim of this study is to investigate the effects...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Mo, Xiao-Dan, Gao, Li-Ping, Wang, Qing-Jun, Yin, Jie, Jing, Yu-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845206/
https://ncbi.nlm.nih.gov/pubmed/29523142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0694-8
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