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Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

BACKGROUND: The fibrillation of islet amyloid polypeptide (IAPP) triggered the amyloid deposition, then enhanced the loss of the pancreatic islet mass. However, it is not clear what factor is the determinant in development of the fibril formation. The aim of this study is to investigate the effects...

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Dettagli Bibliografici
Pubblicato in:Lipids Health Dis
Autori principali: Mo, Xiao-Dan, Gao, Li-Ping, Wang, Qing-Jun, Yin, Jie, Jing, Yu-Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845206/
https://ncbi.nlm.nih.gov/pubmed/29523142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0694-8
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