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Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

BACKGROUND: The fibrillation of islet amyloid polypeptide (IAPP) triggered the amyloid deposition, then enhanced the loss of the pancreatic islet mass. However, it is not clear what factor is the determinant in development of the fibril formation. The aim of this study is to investigate the effects...

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Publicat a:Lipids Health Dis
Autors principals: Mo, Xiao-Dan, Gao, Li-Ping, Wang, Qing-Jun, Yin, Jie, Jing, Yu-Hong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845206/
https://ncbi.nlm.nih.gov/pubmed/29523142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0694-8
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