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Alteration of the tumor stroma using a consensus DNA vaccine targeting Fibroblast Activation Protein (FAP) synergizes with anti-tumor vaccine therapy in mice

PURPOSE: Fibroblast activation protein (FAP) is over-expressed in cancer-associated fibroblasts and is an interesting target for cancer immune therapy, with prior studies indicating a potential to impact the tumor stroma. Our aim was to extend this earlier work through development of a novel FAP imm...

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書目詳細資料
發表在:Clin Cancer Res
Main Authors: Duperret, Elizabeth K., Trautz, Aspen, Ammons, Dylan, Perales-Puchalt, Alfredo, Wise, Megan C., Yan, Jian, Reed, Charles, Weiner, David B.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844837/
https://ncbi.nlm.nih.gov/pubmed/29269377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2033
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