Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT

Immune checkpoint blockade antibodies are setting a new standard of care for cancer patients. It is therefore important to assess any new immune-based therapies in the context of immune checkpoint blockade. Here, we evaluate the impact of combining a synthetic consensus TERT DNA vaccine that has imp...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Duperret, Elizabeth K., Wise, Megan C., Trautz, Aspen, Villarreal, Daniel O., Ferraro, Bernadette, Walters, Jewell, Yan, Jian, Khan, Amir, Masteller, Emma, Humeau, Laurent, Weiner, David B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835021/
https://ncbi.nlm.nih.gov/pubmed/29249395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.11.010
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