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Biophysical and Biological Evaluation of Optimized Stapled Peptide Inhibitors of the Linear Ubiquitin Chain Assembly Complex (LUBAC)
Linear ubiquitylation, in which ubiquitin units are covalently linked through N- and C-terminal amino acids, is a unique cellular signaling mechanism. This process is controlled by a single E3 ubiquitin ligase, the linear ubiquitin chain assembly complex (LUBAC), which is composed of three proteins...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5844832/ https://ncbi.nlm.nih.gov/pubmed/29246782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.11.047 |
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