The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains

The linear ubiquitin chain assembly complex (LUBAC) is the only known ubiquitin ligase for linear/Met1-linked ubiquitin chain formation. One of the LUBAC components, heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1L), was recently shown to catalyse oxyester bond formation between ubiquitin and some sub...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Rodriguez Carvajal, Alan, Grishkovskaya, Irina, Gomez Diaz, Carlos, Vogel, Antonia, Sonn-Segev, Adar, Kushwah, Manish S, Schodl, Katrin, Deszcz, Luiza, Orban-Nemeth, Zsuzsanna, Sakamoto, Shinji, Mechtler, Karl, Kukura, Philipp, Clausen, Tim, Haselbach, David, Ikeda, Fumiyo
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245127/
https://ncbi.nlm.nih.gov/pubmed/34142657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60660
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