Combined vemurafenib and fotemustine in patients with BRAF V600 melanoma progressing on vemurafenib

BACKGROUND: BRAF inhibitor vemurafenib achieves high response rate and an improvement in survival in patients with BRAF-mutated metastatic melanoma. However, median progression-free survival is only 6.9 months in the phase 3 study. Retrospective analyses suggest that treatment with BRAF inhibitors b...

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Publicado en:Oncotarget
Autores principales: Queirolo, Paola, Spagnolo, Francesco, Picasso, Virginia, Spano, Laura, Tanda, Enrica, Fontana, Valeria, Giorello, Laura, Merlo, Domenico Franco, Simeone, Ester, Grimaldi, Antonio Maria, Curvietto, Marcello, Del Vecchio, Michele, Bruzzi, Paolo, Ascierto, Paolo Antonio
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844757/
https://ncbi.nlm.nih.gov/pubmed/29552321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10589
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