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The cryo-electron microscopy structure of human transcription factor IIH

Human transcription factor IIH (TFIIH) is part of the general transcriptional machinery required by RNA polymerase II for the initiation of eukaryotic gene transcription(1). Composed of ten subunits that add up to a molecular mass of about 500 kDa, TFIIH is also essential for nucleotide excision rep...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Greber, Basil J., Nguyen, Thi Hoang Duong, Fang, Jie, Afonine, Pavel V., Adams, Paul D., Nogales, Eva
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844561/
https://ncbi.nlm.nih.gov/pubmed/28902838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23903
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