GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostate cancer stem-like cells in vitro and in vivo

GOLPH2 (also called GP73) is a Golgi glycoprotein, which has been identified as a novel tumor marker upregulated in various cancers, including prostate cancer (PCa). GD55 is a novel GOLPH2-regulated oncolytic adenovirus that exhibits a strong killing effect on hepatoma cells. Here, we investigate th...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Ying, Chang, Xiao, Bo-duan, Qin, Yun, Wang, Bin-rong, Liu, Xin-yuan, Wang, Ru-wei, Fang, Ling, Yan, Hui, Zhou, Xiu-mei, Wang, Yi-gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843840/
https://ncbi.nlm.nih.gov/pubmed/28880012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.91
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