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An oncolytic adenovirus 11p vector expressing adenovirus death protein in the E1 region showed significant apoptosis and tumour-killing ability in metastatic prostate cells

The usefulness for cancer therapy of replication-competent adenoviral vectors expressing therapeutic genes from the E3 region has been evaluated, but few reports have described replication-competent adenoviruses with insertions at the E1 region in the full viral genome. We investigated in different...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Haidong, Mei, Ya-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443017/
https://ncbi.nlm.nih.gov/pubmed/30956777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26754
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