Complete Eradication of Xenograft Hepatoma by Oncolytic Adenovirus ZD55 Harboring TRAIL-IETD-Smac Gene with Broad Antitumor Effect

Cancer-targeting dual-gene virotherapy (CTGVT-DG) is an important modification of CTGVT, in which two suitable genes are used to obtain an excellent antitumor effect. A key problem is to join the two genes to form one fused gene, and then to clone it into the oncolytic viral vector so that only one...

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Autores principales: Wang, Shi-bing, Tan, Yuan, Lei, Wen, Wang, Yi-gang, Zhou, Xiu-mei, Jia, Xiao-yuan, Zhang, Kang-jian, Chu, Liang, Liu, Xin-yuan, Qian, Wen-bin
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440030/
https://ncbi.nlm.nih.gov/pubmed/22530834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.159
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