Synergistic antitumor effects of CDK inhibitor SNS-032 and an oncolytic adenovirus co-expressing TRAIL and Smac in pancreatic cancer

Gene therapy using oncolytic adenoviruses is a novel approach for human cancer therapeutics. The current study aimed to investigate whether the combined use of an adenovirus expressing tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and second mitochondria-derived activator of caspas...

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Publicado no:Mol Med Rep
Main Authors: Ge, Yun, Lei, Wen, Ma, Yingyu, Wang, Yigang, Wei, Buyun, Chen, Xiaoyi, Ru, Guoqing, He, Xianglei, Mou, Xiaozhou, Wang, Shibing
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436152/
https://ncbi.nlm.nih.gov/pubmed/28440486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6472
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