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A hidden talent for a RNA decay factor: UPF1 directs protein decay
The RNA-binding protein, UPF1, is best known as the central factor in the nonsense-mediated RNA decay (NMD) pathway. Feng et al. now report a new function for UPF1 – it is an E3 ubiquitin ligase that specifically promotes the decay of a key pro-muscle transcription factor: MYOD. UPF1 achieves this t...
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| Publicado no: | Bioessays |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843485/ https://ncbi.nlm.nih.gov/pubmed/29236296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700170 |
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