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Structure-mediated RNA decay by UPF1 and G3BP1
Post-transcriptional mechanisms regulate the stability and hence expression of coding and noncoding RNAs. Sequence-specific features within the 3’-untranslated region (3’UTR) often direct mRNAs for decay. Here we characterize a genome-wide RNA decay pathway that reduces the half-lives of mRNAs based...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8055448/ https://ncbi.nlm.nih.gov/pubmed/32017897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.01.021 |
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