The RNA binding protein PTBP1 is necessary for B cell selection in germinal centers

Antibody affinity maturation occurs in germinal centres (GC) where B cells cycle between the light zone (LZ) and the dark zone. In the LZ GC B cells bearing immunoglobulins with the highest affinity for antigen receive positive selection signals from T helper cells that promotes their rapid prolifer...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Immunol
Main Authors: Monzón-Casanova, Elisa, Screen, Michael, Díaz-Muñoz, Manuel D., Coulson, Richard M. R., Bell, Sarah E., Lamers, Greta, Solimena, Michele, Smith, Christopher W.J., Turner, Martin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842895/
https://ncbi.nlm.nih.gov/pubmed/29358707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-017-0035-5
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker