Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation

Polypyrimidine tract binding protein (PTBP1) is a widely expressed RNA binding protein that acts as a regulator of alternative splicing and of cytoplasmic mRNA functions. Vertebrates contain two closely-related paralogs with >75% amino acid sequence identity. Early replacement of PTBP1 by PTBP2 d...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Tan, Lit-Yeen, Whitfield, Peter, Llorian, Miriam, Monzon-Casanova, Elisa, Diaz-Munoz, Manuel D., Turner, Martin, Smith, Christopher W.J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477659/
https://ncbi.nlm.nih.gov/pubmed/25940628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv429
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