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Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination

Testis determination in mammals is initiated by expression of SRY in somatic cells of the embryonic gonad. Genetic analyses in the mouse have revealed a requirement for mitogen-activated protein kinase (MAPK) signaling in testis determination: targeted loss of the kinases MAP3K4 and p38 MAPK causes...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Warr, Nick, Siggers, Pam, Carré, Gwenn-Aël, Wells, Sara, Greenfield, Andy
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842889/
https://ncbi.nlm.nih.gov/pubmed/27009039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.138057
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