Minor Abnormalities of Testis Development in Mice Lacking the Gene Encoding the MAPK Signalling Component, MAP3K1

In mammals, the Y chromosome is a dominant male determinant, causing the bipotential gonad to develop as a testis. Recently, cases of familial and spontaneous 46,XY disorders of sex development (DSD) have been attributed to mutations in the human gene encoding mitogen-activated protein kinase kinase...

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Main Authors: Warr, Nick, Bogani, Debora, Siggers, Pam, Brixey, Rachel, Tateossian, Hilda, Dopplapudi, Asha, Wells, Sara, Cheeseman, Michael, Xia, Ying, Ostrer, Harry, Greenfield, Andy
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086927/
https://ncbi.nlm.nih.gov/pubmed/21559298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019572
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