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Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice

Disorders of sex development in the human population range in severity from mild genital defects to gonadal sex reversal. XY female development has been associated with heterozygous mutations in several genes, including SOX9, WT1 and MAP3K1. In contrast, XY sex reversal in mice usually requires comp...

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書誌詳細
主要な著者: Warr, Nick, Siggers, Pam, Carré, Gwenn-Aël, Bogani, Debora, Brixey, Rachel, Akiyoshi, Mika, Tachibana, Makoto, Teboul, Lydia, Wells, Sara, Sanderson, Jeremy, Greenfield, Andy
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014197/
https://ncbi.nlm.nih.gov/pubmed/24452333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu020
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