Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice

Disorders of sex development in the human population range in severity from mild genital defects to gonadal sex reversal. XY female development has been associated with heterozygous mutations in several genes, including SOX9, WT1 and MAP3K1. In contrast, XY sex reversal in mice usually requires comp...

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Hlavní autoři: Warr, Nick, Siggers, Pam, Carré, Gwenn-Aël, Bogani, Debora, Brixey, Rachel, Akiyoshi, Mika, Tachibana, Makoto, Teboul, Lydia, Wells, Sara, Sanderson, Jeremy, Greenfield, Andy
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014197/
https://ncbi.nlm.nih.gov/pubmed/24452333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu020
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