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The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion
Robust innate immune detection of rapidly evolving pathogens is critical for host defense. Nucleotide-binding domain leucine-rich repeat (NLR) proteins function as cytosolic innate immune sensors in plants and animals. However, the structural basis for ligand-induced NLR activation has so far remain...
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| Veröffentlicht in: | Science |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842810/ https://ncbi.nlm.nih.gov/pubmed/29146805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao1140 |
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