Structural basis for specific flagellin recognition by the NLR protein NAIP5

The nucleotide-binding domain- and leucine-rich repeat (LRR)-containing proteins (NLRs) function as intracellular immune receptors to detect the presence of pathogen- or host-derived signals. The mechanisms of how NLRs sense their ligands remain elusive. Here we report the structure of a bacterial f...

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Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Yang, Xinru, Yang, Fan, Wang, Weiguang, Lin, Guangzhong, Hu, Zehan, Han, Zhifu, Qi, Yijun, Zhang, Liman, Wang, Jiawei, Sui, Sen-Fang, Chai, Jijie
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752844/
https://ncbi.nlm.nih.gov/pubmed/29182158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.148
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