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Enzymatic Self-Assembly Confers Exceptionally Strong Synergism with NF-κB Targeting for Selective Necroptosis of Cancer Cells

As a promising molecular process for selectively inhibiting cancer cells without inducing acquired drug resistance, enzyme-instructed self-assembly (EISA) usually requires relatively high dosages. Despite its discovery 30 years ago, the translation of the knowledge about NF-κB signaling into clinic...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Zhou, Jie, Du, Xuewen, Chen, Xiaoyi, Wang, Jiaqing, Zhou, Ning, Wu, Difei, Xu, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842673/
https://ncbi.nlm.nih.gov/pubmed/29377688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12368
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