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Minimal C-Terminal Modification Boosts Peptide Self-Assembling Ability for Necroptosis of Cancer Cells
Here we reported the first case that enhancing self-assembling ability boosts anti-cancer efficacy through simple and minimal modification of C-terminal of a D-tripeptide. By only 2% change of the molecular weight, this facile approach increases the inhibitory activity over an order of magnitude (IC...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855835/ https://ncbi.nlm.nih.gov/pubmed/27087169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc02282k |
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