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Enzymatic self-assembly of an immunoreceptor tyrosine-based inhibitory motif (ITIM)

Here we show the first example of an immunoreceptor tyrosine-based inhibitory motif (ITIM), LYYYYL, as well as its enantiomeric or retro-inverso peptide, to self-assemble in water via enzyme-instructed self-assembly. Upon enzymatic dephosphorylation, the phosphohexapeptides become hexapeptides, whic...

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Bibliografiske detaljer
Udgivet i:Org Biomol Chem
Main Authors: Yamagata, Natsuko Nina, Chen, Xiaoyi, Zhou, Jie, Li, Jie, Du, Xuewen, Xu, Bing
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561744/
https://ncbi.nlm.nih.gov/pubmed/28675212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob01074e
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