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Enzymatically-Formed Peptide Assemblies Sequestrate Proteins and Relocate Inhibitors for Selectively Killing Cancer Cells
Here we show that enzymatic reaction generates peptide assemblies to sequestrate proteins for selectively killing cancer cells. A phosphopeptide bearing the antagonistic motif (AVPI) to the inhibitors of apoptotic proteins (IAPs) enters cancer cells and normal cells via caveolin-dependent endocytosi...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7844580/ https://ncbi.nlm.nih.gov/pubmed/32521103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006290 |
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