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Enzymatic Assemblies of Thiophosphopeptides Instantly Target Golgi Apparatus and Selectively Kill Cancer Cells

Golgi apparatus is emerging as a key signaling hub of cells and an important target for cancer therapy, but there are few approaches for targeting Golgi and selectively killing cancer cells. Here we show an unexpected result that changing an oxygen atom of the phosphoester bond in phosphopeptides by...

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Dettagli Bibliografici
Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Tan, Weiyi, Zhang, Qiuxin, Wang, Jiaqing, Yi, Meihui, He, Hongjian, Xu, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159897/
https://ncbi.nlm.nih.gov/pubmed/33783926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202102601
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