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Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit
AMPA receptor (AMPAR) trafficking is a key determinant of synaptic strength and synaptic plasticity. Under basal conditions, constitutive trafficking maintains surface AMPARs by internalization into the endosomal system, where the majority are sorted and targeted for recycling back to the plasma mem...
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| Publicado no: | Sci Rep |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841360/ https://ncbi.nlm.nih.gov/pubmed/29515177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22542-z |
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