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The GluA1 AMPAR subunit is necessary for hedonic responding but not hedonic value in female mice

The GluA1 subunit of the AMPA receptor has been implicated in anhedonia. Mice that lack GluA1 (Gria1 knockout mice) show reduced lick cluster size, a measure of palatability in feeding behaviour. This deficit may reflect a role for GluA1 in encoding the hedonic value of palatable substances or inste...

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Udgivet i:Physiol Behav
Main Authors: Strickland, Jasmin A., Austen, Joseph M., Sprengel, Rolf, Sanderson, David J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768090/
https://ncbi.nlm.nih.gov/pubmed/33058902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2020.113206
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