PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease

Mitochondrial dysfunction and synaptic damage are early pathological features of the Alzheimer’s disease-affected brain. Memory impairment in Alzheimer’s disease is a manifestation of brain pathologies such as accumulation of amyloid-β peptide and mitochondrial damage. The underlying pathogenic mech...

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Publicado en:Brain
Autores principales: Du, Fang, Yu, Qing, Yan, Shijun, Hu, Gang, Lue, Lih-Fen, Walker, Douglas G, Wu, Long, Yan, Shi Fang, Tieu, Kim, Yan, Shirley ShiDu
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841141/
https://ncbi.nlm.nih.gov/pubmed/29077793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx258
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