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PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease
Mitochondrial dysfunction and synaptic damage are early pathological features of the Alzheimer’s disease-affected brain. Memory impairment in Alzheimer’s disease is a manifestation of brain pathologies such as accumulation of amyloid-β peptide and mitochondrial damage. The underlying pathogenic mech...
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| Publicado no: | Brain |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841141/ https://ncbi.nlm.nih.gov/pubmed/29077793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx258 |
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