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Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer’s Disease Trans-Mitochondrial Cybrid Cells

Mitochondrial dysfunction and axonal degeneration are early pathological features of Alzheimer’s disease (AD)-affected brains. The underlying mechanisms and strategies to rescue it have not been well elucidated. Here, we evaluated axonal mitochondrial transport and function in AD subject-derived mit...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Yu, Qing, Fang, Du, Swerdlow, Russell Howard, Yu, Haiyang, Chen, John Xi, Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562501/
https://ncbi.nlm.nih.gov/pubmed/27567872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160532
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