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Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

Mitochondrial dysfunction is an early pathological feature of Alzheimer’s disease (AD). The underlying mechanisms and strategies to repair it remain unclear. Here, we demonstrate for the first time the direct consequences and potential mechanisms of mitochondrial functional defects associated with a...

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Bibliografske podrobnosti
Main Authors: Gan, Xueqi, Huang, Shengbin, Wu, Long, Wang, Yongfu, Hu, Gang, Li, Guangyue, Zhang, Hongju, Yu, Haiyang, Swerdlow, Russell Howard, Chen, John Xi, Yan, Shirley ShiDu
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991235/
https://ncbi.nlm.nih.gov/pubmed/24252614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.11.009
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