Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

Mitochondrial dysfunction is an early pathological feature of Alzheimer’s disease (AD). The underlying mechanisms and strategies to repair it remain unclear. Here, we demonstrate for the first time the direct consequences and potential mechanisms of mitochondrial functional defects associated with a...

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Detalhes bibliográficos
Main Authors: Gan, Xueqi, Huang, Shengbin, Wu, Long, Wang, Yongfu, Hu, Gang, Li, Guangyue, Zhang, Hongju, Yu, Haiyang, Swerdlow, Russell Howard, Chen, John Xi, Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991235/
https://ncbi.nlm.nih.gov/pubmed/24252614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.11.009
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