F(1)F(0) ATP Synthase–Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline

Mitochondrial abnormalities are well known to cause cognitive decline. However, the underlying molecular basis of mitochondria-associated neuronal and synaptic dysfunction in the diabetic brain remains unclear. Here, using a mitochondrial single-channel patch clamp and cyclophilin D (CypD)-deficient...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Yan, Shijun, Du, Fang, Wu, Long, Zhang, Zhihua, Zhong, Changjia, Yu, Qing, Wang, Yongfu, Lue, Lih-Fen, Walker, Douglas G., Douglas, Justin T., Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079631/
https://ncbi.nlm.nih.gov/pubmed/27554467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0556
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