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Synergistic Exacerbation of Mitochondrial and Synaptic Dysfunction and Resultant Learning and Memory Deficit in a Mouse Model of Diabetic Alzheimer’s Disease

Diabetes is considered to be a risk factor in Alzheimer’s disease (AD) pathogenesis. Although recent evidence indicates that diabetes exaggerates pathologic features of AD, the underlying mechanisms are not well understood. To determine whether mitochondrial perturbation is associated with the contr...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Wang, Yongfu, Wu, Long, Li, Jianping, Fang, Du, Zhong, Changjia, Chen, John Xi, Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466096/
https://ncbi.nlm.nih.gov/pubmed/25096625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140972
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