Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer

Metabolic reprogramming is widely known as a hallmark of cancer cells to allow adaptation of cells to sustain survival signals. In this report, we describe a novel oncogenic signaling pathway exclusively acting in mutated epidermal growth factor receptor (EGFR) non‐small cell lung cancer (NSCLC) wit...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Ali, Azhar, Levantini, Elena, Teo, Jun Ting, Goggi, Julian, Clohessy, John G, Wu, Chan Shuo, Chen, Leilei, Yang, Henry, Krishnan, Indira, Kocher, Olivier, Zhang, Junyan, Soo, Ross A, Bhakoo, Kishore, Chin, Tan Min, Tenen, Daniel G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840543/
https://ncbi.nlm.nih.gov/pubmed/29449326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708313
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