Yeast surface display platform for rapid discovery of conformationally selective nanobodies

Camelid single-domain antibody fragments (“nanobodies”) provide the remarkable specificity of antibodies within a single 15 kDa immunoglobulin V(HH) domain. This unique feature has enabled applications ranging from use as biochemical tools to therapeutic agents. Nanobodies have emerged as especially...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Struct Mol Biol
Autori principali: McMahon, Conor, Baier, Alexander S., Pascolutti, Roberta, Wegrecki, Marcin, Zheng, Sanduo, Ong, Janice X., Erlandson, Sarah C., Hilger, Daniel, Rasmussen, Søren G. F., Ring, Aaron M., Manglik, Aashish, Kruse, Andrew C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839991/
https://ncbi.nlm.nih.gov/pubmed/29434346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0028-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi