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Telomerase Reverse Transcriptase Promoter Alterations Across Cancer Types as Detected by Next-Generation Sequencing: A Clinical and Molecular Analysis of 423 Patients

BACKGROUND: Telomerase reverse transcriptase (TERT) promoter mutations that may affect telomerase activity have recently been described in human malignancies. The purpose of this study was to investigate the clinical correlates of TERT promoter abnormalities in a large cohort of patients with divers...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer
Main Authors: Schwaederle, Maria, Krishnamurthy, Nithya, Daniels, Gregory A., Piccioni, David E., Kesari, Santosh, Fanta, Paul T., Schwab, Richard B., Patel, Sandip P., Parker, Barbara A., Kurzrock, Razelle
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839978/
https://ncbi.nlm.nih.gov/pubmed/29211306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31175
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