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Telomerase Reverse Transcriptase Promoter Alterations Across Cancer Types as Detected by Next-Generation Sequencing: A Clinical and Molecular Analysis of 423 Patients

BACKGROUND: Telomerase reverse transcriptase (TERT) promoter mutations that may affect telomerase activity have recently been described in human malignancies. The purpose of this study was to investigate the clinical correlates of TERT promoter abnormalities in a large cohort of patients with divers...

詳細記述

保存先:
書誌詳細
出版年:Cancer
主要な著者: Schwaederle, Maria, Krishnamurthy, Nithya, Daniels, Gregory A., Piccioni, David E., Kesari, Santosh, Fanta, Paul T., Schwab, Richard B., Patel, Sandip P., Parker, Barbara A., Kurzrock, Razelle
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839978/
https://ncbi.nlm.nih.gov/pubmed/29211306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31175
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