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Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects
Neural tube defects (NTDs) remain one of the most serious birth defects, and although genes in several pathways have been implicated as risk factors for neural tube defects via knockout mouse models, very few molecular causes in humans have been identified. Whole exome sequencing identified deleteri...
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| Publicado no: | Eur J Hum Genet |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5838979/ https://ncbi.nlm.nih.gov/pubmed/29358613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0025-y |
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