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Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

Although apoptosis has been extensively studied in developing neurons, the dynamic changes in this pathway after neuronal maturation remain largely unexplored. We show that as neurons mature, cytochrome c– mediated apoptosis progresses from inhibitor of apoptosis protein–dependent to –independent re...

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Detalhes bibliográficos
Main Authors: Wright, Kevin M., Smith, Michelle I., Farrag, Lila, Deshmukh, Mohanish
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099178/
https://ncbi.nlm.nih.gov/pubmed/18056406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708086
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