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Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

Although apoptosis has been extensively studied in developing neurons, the dynamic changes in this pathway after neuronal maturation remain largely unexplored. We show that as neurons mature, cytochrome c– mediated apoptosis progresses from inhibitor of apoptosis protein–dependent to –independent re...

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Autors principals: Wright, Kevin M., Smith, Michelle I., Farrag, Lila, Deshmukh, Mohanish
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099178/
https://ncbi.nlm.nih.gov/pubmed/18056406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708086
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