Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

Although apoptosis has been extensively studied in developing neurons, the dynamic changes in this pathway after neuronal maturation remain largely unexplored. We show that as neurons mature, cytochrome c– mediated apoptosis progresses from inhibitor of apoptosis protein–dependent to –independent re...

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Bibliographic Details
Main Authors: Wright, Kevin M., Smith, Michelle I., Farrag, Lila, Deshmukh, Mohanish
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099178/
https://ncbi.nlm.nih.gov/pubmed/18056406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708086
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